BDBM25870 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile::CHEMBL549::CITALOPRAM::CITALOPRAM HYDROBROMIDE::Escitalopram::[3H]Citalopram::[3H]Cytalopram::[3H]Escitalopram::[3H]Lexapro

SMILES CN(C)CCCC1(OCc2cc(ccc12)C#N)c1ccc(F)cc1

InChI Key InChIKey=WSEQXVZVJXJVFP-UHFFFAOYSA-N

Data  130 KI  25 IC50  1 EC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 25870   

TargetSodium-dependent noradrenaline transporter(MOUSE)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)
Affinity DataKi: >1.00E+3nMAssay Description:Tested in vitro for norepinephrine (NE) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)
Affinity DataKi:  4.07E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)
Affinity DataKi:  4.87E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)
Affinity DataKi:  5.03E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)
Affinity DataKi:  6.19E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)
Affinity DataKi:  6.19E+3nMAssay Description:In vitro binding affinity of the compound was determined against human norepinephrin transporter in human embryonic kidney cell line by using [3H]-ni...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)
Affinity DataKi:  6.51E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)
Affinity DataKi:  7.84E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)
Affinity DataKi:  7.87E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)
Affinity DataKi:  8.69E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of [3H]dopamine uptake at human NET expressed in COS7 cells after 5 mins by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank